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Results of the first phase of the Ceramide Ring Trial have been published in Nature Communications, representing a significant landmark in the field of lipidomics.

This achievement, involving researchers at the University of Vienna and scientific teams in Singapore, Julich and Espoo, represents an advance in the establishment of ceramide reference values, plasma lipids involved in diseases such as cardiovascular diseases. The ring trial was performed under the umbrella of the International Lipidomics Society (ILS).

Lipidomics—the large-scale study of pathways and networks of cellular lipids in biological systems—aims to understand the roles of lipids in health and disease by analyzing their structures, functions, and interactions in cells. Understanding the upper and lower concentration boundaries of lipids is essential for scientific progress and the translation of technology within lipidomics.

To do this, the Ceramide Ring Trial was initiated as the first step in addressing technical replication across a global network of laboratories.

A ring trial is a method where multiple laboratories independently analyze the same samples using similar or different methods to compare their results. It helps assess the reliability and consistency of measurements across different labs, improving standardization and quality control in scientific testing.

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