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Mitragyna diversifolia is an evergreen shrub or small tree that grows up to 5 m in height, found in moist and wet forests, as well as in disturbed habitats. Available phytochemical studies suggest that the main constituents of M. diversifolia are triterpenoids and alkaloids.

In a study published in Biomedicine & Pharmacotherapy, researchers from Xishuangbanna Tropical Botanical Garden (XTBG) of the Chinese Academy of Sciences isolated compounds from the branches of Mitragyna diversifolia and investigated their potential antidiabetic and antioxidant activities.

They isolated 16 compounds, including 12 triterpenoids (1–12), one phenolic compound (13), and three flavonoids (14–16).

"Compounds 1–7, and 10–16 were isolated from M. diversifolia for the first time," said Zhang Yumei, corresponding author of this study and a researcher from XTBG.

Previous studies have shown that inhibiting the activity of α-glucosidase and increasing glucose uptake by organs or tissues are important strategies for type 2 diabetes mellitus (T2DM) patients to maintain appropriate blood glucose levels.

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