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Two teams that rank outside the top 20 in scoring will meet on Sunday when the Broncos host the Chargers during the Week 6 NFL schedule. Denver is averaging just 19.2 points per game, but it has been able to overcome its poor offense and rattle off a three-game winning streak. The Chargers have lost back-to-back games, although they had an extra week to prepare for this contest. They are 3-point road favorites in the Week 6 NFL odds, as they try to snap a five-game losing skid at Mile High.

There are five other Week 6 NFL spreads that are lined at three points or smaller, including a Monday Night Football showdown between the Bills (-2.5) and Jets, who just fired head coach Robert Saleh. Before you make any Week 6 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2024 NFL season on an incredible 10-2 hot streak on top-rated NFL picks this year. Longer term, it is on a 191-131 roll on top-rated NFL picks that dates back to the 2017 season and a 45-23 roll on top-rated NFL picks since Week 7 of 2022.

Now, the model has scoured the Week 6 NFL odds and locked in five confident NFL best bets. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 6 NFL picks at SportsLine.

Top Week 6 NFL picks

After simulating every game 10,000 times, the model is high on the Green Bay Packers (-5.5, 49.5) to cover at home against the Arizona Cardinals. The Cardinals are coming off an upset win at San Francisco last week, but they have only won five of their last 19 games dating back to last season. They are heading to a city where they have not had much success, losing seven of their previous eight trips to Lambeau Field.

Green Bay enters Week 6 with a winning record following its 24-19 road win against the Rams last week, as quarterback Jordan Love helped the Packers secure the win with a pair of third-quarter touchdown passes. Love has gone over 220 passing yards in all three of his starts this season, including a 389-yard performance with four touchdowns against the Vikings two weeks ago. The Packers have covered the spread in seven of their last nine games, and they are covering in over 60% of the model’s latest simulations this week. See which other NFL parlay picks to make here.

How to make Week 6 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including two underdogs that win outright, defying oddsmakers everywhere. You can only see the model’s NFL Week 6 best bets and parlay at SportsLine.

What are the model’s top Week 6 NFL picks, and which NFL matchups should you target for an epic 25-1 payout? Visit SportsLine now to see the Week 6 NFL best bets from a model on an 191-131 run on top-rated picks, and find out.

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